OnyxMD Journal
Evidence-based education on performance, wellness, and treatment options — written by our medical team.
April 27, 2026
Morning erections and erectile dysfunction can reflect sleep quality, testosterone signaling, nerve function, and vascular health in men.
April 26, 2026
Mediterranean diet and erectile dysfunction are linked through vascular health, inflammation, and metabolic risk. Learn what studies suggest for men.
April 25, 2026
Antidepressants and erectile dysfunction are commonly linked. Learn how SSRIs may affect arousal, erections, and treatment decisions.
April 24, 2026
Clinical evidence on pelvic floor exercises for erectile dysfunction, how the bulbocavernosus and ischiocavernosus muscles sustain erections, and what the research shows.
April 23, 2026
How dopamine pathways in the brain regulate erectile function, why central nervous system signaling matters for sexual arousal, and what clinical research shows.
April 22, 2026
Tadalafil and pycnogenol for erectile dysfunction may pair PDE5 inhibition with endothelial support. Review the evidence, timing, safety, and candidate fit.
April 21, 2026
Blood pressure medication and erectile dysfunction can overlap, but hypertension itself is often the bigger driver. Learn what recent studies suggest.
April 20, 2026
High cholesterol and erectile dysfunction are linked through endothelial injury, inflammation, and reduced penile blood flow. Learn what recent studies suggest.
April 19, 2026
Metabolic syndrome and erectile dysfunction are linked through abdominal fat, insulin resistance, and blood pressure. Learn what current studies suggest.
April 18, 2026
Daily ED treatment with tadalafil, vardenafil, vitamin D3, and K2 may support steadier response. Review the clinical rationale, evidence, and safety.
April 18, 2026
Mach 1 dual therapy combines sildenafil and tadalafil in one physician-supervised plan. Here is why that combination can make sense for stronger, longer on-demand ED support.
April 17, 2026
Exercise and erectile dysfunction are linked through circulation, endothelial function, and insulin sensitivity. Learn what training may mean for erections.
April 16, 2026
Maximum-strength ED treatment pairs sildenafil 70 mg with tadalafil 20 mg. Review the pharmacology, timing, safety, and evidence behind this profile.
April 15, 2026
Alcohol and erectile dysfunction are linked through vascular, hormonal, and neurologic pathways. Learn what heavy and chronic drinking may mean for erections.
April 14, 2026
Sublingual ED treatment may combine apomorphine with tadalafil and vardenafil. Review the evidence, dosing strategy, safety, and clinical candidate selection.
April 13, 2026
Nicotine and erectile dysfunction are linked through vascular injury and autonomic effects. Review what smoking, vaping, and quitting may mean for erections.
April 12, 2026
Erectile dysfunction in younger men is often multifactorial. Review the clinical evidence on stress, sleep, metabolic health, and when to seek care.
April 11, 2026
Obesity and erectile dysfunction are closely linked through waist size, vascular health, insulin resistance, and inflammation. Here is what studies suggest.
April 10, 2026
Tadalafil and pycnogenol for ED may support erections through PDE5 inhibition and endothelial function. Review the clinical evidence, rationale, and safety.
April 8, 2026
Daily chewable tadalafil and vardenafil for ED may support steadier response. Review the clinical rationale, nutrient context, and safety considerations.
April 7, 2026
Sleep apnea and erectile dysfunction are closely linked through hypoxia, endothelial dysfunction, and hormone disruption. Here's what current evidence shows.
April 6, 2026
Sildenafil and tadalafil together for ED may offer complementary support in select men. Review the evidence, pharmacology, and clinical considerations.
April 5, 2026
High blood pressure and erectile dysfunction often share the same vascular roots. Learn what the evidence says about circulation, risk, and treatment.
April 4, 2026
Men with diabetes are 2–5× more likely to develop erectile dysfunction. This article explains the mechanisms behind diabetic ED and what clinical evidence shows about treatment.
April 3, 2026
Clinical research links vitamin D deficiency to impaired erectile function via endothelial dysfunction and reduced nitric oxide. Here's what the evidence shows.
April 2, 2026
Chronic stress elevates cortisol, suppressing testosterone and disrupting penile vascular function. Explore the clinical mechanisms linking stress and erectile dysfunction.
March 31, 2026
A deep dive into VAST's triple-mechanism formula, sublingual Apomorphine 3mg, Tadalafil 20mg, and Vardenafil 15mg, and the science that makes it different.
March 30, 2026
Alcohol and erectile dysfunction are clinically linked. Learn how drinking impairs nitric oxide, testosterone, and vascular function, and what the research says.
March 29, 2026
Oxidative stress silently damages the vascular tissue behind erections. Learn how free radicals impair erectile function and what clinical research says about antioxidant interventions.
March 28, 2026
Clinical research shows aerobic exercise may improve erectile function. Learn how physical activity affects nitric oxide, blood flow, and ED, and what men can do.
March 27, 2026
On-demand tadalafil for erectile dysfunction may work even better with vascular support. Learn the science behind OnyxMD Red Pill, tadalafil, and Pycnogenol.
March 26, 2026
Poor sleep and erectile dysfunction are clinically linked. Learn how sleep deprivation disrupts testosterone, nocturnal erections, and sexual performance.
March 25, 2026
Performance anxiety is a leading cause of erectile dysfunction in younger men. Learn what the research says and which treatment approaches are most effective.
March 23, 2026
Low testosterone may be silently driving your ED. Learn how androgen deficiency affects erectile function, what the research says, and what treatment options exist.
March 22, 2026
Nitric oxide is the master signaling molecule behind erectile function. Learn how NO drives blood flow, why it declines with age, and what clinical evidence says about restoring it.
March 21, 2026
A deep dive into EPIQ CHEWS, OnyxMD's daily chewable combining Tadalafil 5mg, Vardenafil 5mg, Vitamin D3, and K2 for sustained erectile health support.
March 21, 2026
A straightforward guide to getting an ED prescription through telehealth, how the process works, what doctors evaluate, what to avoid, and how to choose a legitimate provider.
March 21, 2026
A clinical comparison of sildenafil (Viagra) and tadalafil (Cialis), how they work, how long they last, side effects, and which PDE5 inhibitor may be the better fit for your lifestyle.
March 21, 2026
Emerging research links daily tadalafil use to reduced cardiovascular mortality, improved endothelial function, and lower blood pressure. Here's what the clinical evidence shows.
March 20, 2026
OnyxMD Red Pill combines Tadalafil 20mg with Pycnogenol 70mg for on-demand ED treatment. Explore the clinical science behind this dual-mechanism formulation.
March 19, 2026
Mach 1 combines Sildenafil 70mg and Tadalafil 20mg for maximum-strength ED treatment. Explore the clinical science behind dual PDE5 inhibition and who it's designed for.
March 17, 2026
New guidelines classify erectile dysfunction as a cardiovascular risk marker. Learn what the science says and what it means for your long-term health.
March 15, 2026
Clinical evidence on combining tadalafil and vardenafil for erectile dysfunction, why dual PDE5 therapy may outperform single-agent treatment for many men.
March 13, 2026
Vitamin D deficiency is linked to erectile dysfunction through endothelial and hormonal pathways. Here's what the latest clinical research reveals and what you can do.
March 11, 2026
Vardenafil for erectile dysfunction offers one of the fastest onsets of any PDE5 inhibitor. Here's what the clinical evidence says about how it works and who benefits most.
March 9, 2026
Discover how daily tadalafil 5mg works, what clinical research reveals about its efficacy, and why once-daily dosing is changing how men manage ED.
March 9, 2026
Daily tadalafil 5mg offers sustained erectile function without the planning. Here's what recent clinical research reveals about once-daily dosing for men with ED.
January 14, 2026
EPIQ CHEWS deliver daily tadalafil 5mg + vardenafil 5mg via buccal absorption, improving endothelial function, reducing vascular inflammation, and outperforming on-demand pills. Here's the evidence.